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There were no SAEs, vision disturbances, or clinically significant changes from baseline in vital signs, electrocardiograms, or laboratory panels.

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This activity has been planned and implemented in accordance with Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of Medical Education Collaborative and Medscape, Inc.

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A selective inhibitor of CYP3A4, ketoconazole, increased tadalafil AUC by 107% and a CYP3A4 inducer, rifampicin, reduced tadalafil AUC by 88%, relative to the AUC values for tadalafil (10 mg) alone (see Warnings and Precautions).

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Actions Pharmacotherapeutic group: medicines used in erectile dysfunction.